September 3, 2026

Cardiawave is proud to share the publication in Circulation of the 12-month results from the Pivotal study evaluating Valvosoft®, Cardiawave’s noninvasive ultrasound therapy for patients with severe symptomatic calcific aortic stenosis who are not recommended for an immediate valve replacement procedure.
 
This prospective multicenter study, conducted across 11 European centers, highlights the potential of noninvasive ultrasound therapy to address an important unmet need for frail patients with limited treatment options.
 
Thanks to all investigators, clinical teams, and especially the patients and their families whose participation made this work possible.
 
This publication marks another important milestone in Cardiawave’s mission to bring a new therapeutic option to patients living with calcific aortic stenosis.
 
🔗 Read the publication: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.125.077582