An immense unmet
medical need: Aortic Stenosis

A non-invasive therapy to treat Aortic Stenosis

Quality of life improvement

CARDIAWAVE

Cardiawave has developed a unique non-invasive ultrasound therapy for the treatment of calcific aortic stenosis.

MISSION AND VALUES

Our mission is to improve the quality of patient care by offering medical devices for non-invasive therapies.

CAREERS

Discover our job offers!

AORTIC STENOSIS

Aortic stenosis is one of the most common and serious valve disease problems. It is a life-threatening disease caused by the narrowing of the opening of the aortic valve.

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3rd
  • most frequent cardiovascular disease in developed countries (1) (2).

800,000
  • number of elderly patients with severe symptomatic aortic stenosis in North America in 2025 and 1.4 million in 2050 ; 1.3 millon in Europe in 2025 and 2.1 million in 2050 (3).

US$5.6bn
  • health spending to treat symptomatic aortic valve disease in the United States of America (4).

65%
  • of severe symptomatic aortic stenosis patients remain untreated in the United States of America (5).

1 Durko AP, et al. Annual number of candidates for transcatheter aortic valve implantation per country: current estimates and future projections. European Heart Journal. July 01, 2018; 39(28):2635-2642. (DOI: 10.1093/eurheartj/ehy107)
2 Lindman B, et al. Calcific Aortic Stenosis. Nature Reviews Disease Primers 2, Article number: 16006. March 03, 2016. (DOI: 10.1038/nrdp.2016.6)
3 Osnabrugge R., et al. Aortic Stenosis in the Elderly: Disease Prevalence and Number of Candidates for Transcatheter Aortic Valve Replacement: A Meta-Analysis and Modeling Study. Journal of American College of Cardiology, Volume 62, Issue 11, Pages 1013-1014. September 2013. (DOI: 10.1016/j.jacc.2013.05.015)
4 Moore M, et al. The direct health-care burden of valvular heart disease: evidence from US national survey data. Clinicoeconomics and Outcomes Research. October 18, 2016; 8:613-627 (DOI: 10.2147/CEOR.S112691).
5 Wood S. Vast Numbers of Severe Symptomatic AS Patients Untreated? A Plea and Some Pushback. TCTMD. June 14, 2019.

NON-INVASIVE THERAPY

To treat aortic stenosis, Cardiawave has developed a real-time image-guided non-invasive ultrasound therapy using a cutting-edge ultrasound technology.

Non-Invasive Ultrasound Therapy (NIUT) consists in repairing the aortic valve, not replacing it. No surgery is required. Truly non-invasive.

NEWS

FUNDINGS

This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 829492.

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This project has received funding from the Innov’Up of the Ile-de-France region program under grant agreement No DOS0133065/00.

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This project is supported by the French Government, managed by the National Research Agency (ANR) under the program “Investissements d’avenir” with the reference ANR-16-RHUS-0003.

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