CARDIAWAVE

ABOUT CARDIAWAVE

Cardiawave was created at the end of 2014 as a result of a partnership of several years between the academic laboratories Physics for Medicine Paris (INSERM/CNRS/ESPCI/PSL) and Langevin Institute (CNRS/INSERM/ESPCI), world leaders in ultrasound imaging and therapy, and the Georges Pompidou European Hospital (HEGP), a leader in the field of valve disease and cardiac ultrasound imaging. Member of the national research consortium RHU Stop-AS and of the competitiveness cluster MEDICEN Paris Région, Cardiawave has secured over €22M in funding since its inception.

With a quality management system, EN ISO 13485:2016 certified since 2019, Cardiawave has developed a non-invasive ultrasound therapy (NIUT) medical device for the treatment of Calcific Aortic Stenosis (CAS), an investigational device. CAS is the most prevalent heart valve disease in adults and one of the most common causes of cardiovascular mortality worldwide.  Early 2019, Cardiawave was granted approval to perform a first-in-human feasibility and safety clinical study (FIH‑I) in France and in the Netherlands to enrol 10 patients. Another study (FIH-II) has been approved in Serbia and started at the end of 2019. In 2020, Cardiawave obtained approval for an extension of its FIH-I increasing the study population up to 30 patients. These studies are still ongoing (FIH-I inclusion being completed). A Research Letter presenting the preliminary clinical results of the first 10-patients included in FIH-I has been published in Circulation on January 25, 2021.

Our mission is to improve the quality of patient care by offering medical devices
for non-invasive therapies.

AWARDS & HONOURS

Cardiawave has won several awards and honours since its inception.

2021

Accelerator & Showcase Cohort

MedTech Innovator

2021

HealthTech Award, best concept / invention

Nobel Project – MedTech Forum 2021

2020

Tech Tour finalists

Tech Tour Health 2020

2019

« Best Fit to the US market », pitch contest in Boston

Care Tour

2019

Prize-winner of the International Symposium on Therapeutic Ultrasound: Student Award

ISTU / Barcelona

2018

Prize-winner of Gallien MedStart’Up, in the category: Best Collaboration with Academia Leading to a Breakthrough Solution, partnering with Mount Sinai Medical Center New York

USA

2018

Prize-winner of SME Instrument, Phase2

European Union

2017

Prize-winner of Worldwide Innovation Contest (CMI), 3rd phase

French government / BPI France

2015

Prize-winner of Worldwide Innovation Contest (CMI), 2nd phase

French government / BPI France

2015

Prize winner of Fondation pour l’Innovation Thérapeutique Béatrice Denys

Turenne Capital (French Investment Fund)

2014

Prize-winner of Worldwide Innovation Contest (CMI), 1st phase

French government / BPI France

2014

Prize-winner of the French National Contest for Innovative Technologies Companies

French government / BPI France